Novartis - For use in healthy cattle as an aid in the prevention of coibacillosis in calves caused by Escherichia coli. Dosage and Administration: Shake well before and during use. Administer 1 ml dose of bacterin intramuscularly in the upper neck region of breeding stock. Vaccinate dairy cows during the dry-off period. Revaccinate annually. A single dose of Bovine Pili Shield, given 12 months to 8 weeks prior to calving, helps prevent calf scours caused by E. coli K99. 60 day withdrawal.